Institute of Biophysics
The Institute of Biophysics of Ilia State University is a research institution with the aim of conducting research in the latest trends and areas of Biophysics: Molecular Biophysics, Biophysics of Photobiological Processes, and Biotechnology. Research is being conducted in partnership with the globally recognized leading scientific and technological centers (Ohio State University (US), Copernicus University (Poland), Lawrence Berkeley National Laboratory (USA).
The Institute aims to integrate a research component into the university environment. Along with the academic staff involved in research projects, Ilia State University doctoral, graduate and undergraduate degree students are also engaged in the aforementioned projects. Together with the research component, the activities of the institute comprise general and special courses at bachelor’s degree programmes, and master’s and doctoral programmes for students interested in Biophysics. Institute offers public lectures, conferences and summer schools in which local and foreign scientists will be involved.
Publications
2020
- Gvarjaladze D., Gulua T., Gogichaishvili Sh., Hritz J., Metreveli N. „Quadruplex Priming Amplification at a Range of Human Body Temperature.” Biointerface Research in Applied Chemistry. Volume 11, Issue 1. Online: 07.2020.
- Kankia, “Quadruplex-Based Reactions for Dynamic DNA Nanotechnology” J. Phys. Chem. B 124, 4263-4269 (2020).
- Midodashvili P. and Midodashvili L., The 6D Standing Wave Braneworld with Real Scalar Field, Braz. J. Phys. 50 (2020) 750.
- Olia Rcheulishvili, Lia Tsverava, Revaz Solomonia, Nunu Metreveli, Aleksandre Rcheulishvili, Lela Tugushi, Manana Gurielidze; Proteomic Responses of oxidative stress-resistant Arthrobacter globiformis 151B to Cr and Mg and the Influence of Mg on the Uptake Process of Cr(III) and Cr(VI); Annals of Agrarian Sciences; (2020).
- Olia Rcheulishvili, Nunu Metreveli, Aleksandre Rcheulishvili, Lela Tugushi, Manana Gurielidze; Reduction and uptake of Cr(VI) by Arthrobacter oxydans and uptake of Cr(III) by Arthrobacter 61B under the influence of potassium and magnesium; Annals of Agrarian Sciences; (2020).
2019
- B. Kankia, “Stability Factors of the Parallel Quadruplexes: DNA versus RNA” J. Phys. Chem. B 123, 1060-1067 (2019).
- O.Rcheulishvili, L.Tsverava, A. Rcheulishvili, M. Gurielidze, R. Solomonia, N. Metreveli, N. Jojua, H-Y. Holman;” Heavy metals specific proteomic responses of a highly resistant Arthrobacter globiformis 151B”, Annals of Agrarian Science, 17 (2019) 218-229.
- V. G. Bregadze, I. G. Khutsishvili, T. B. Khuskivadze, Z. G. Melikishvili, T. G. Giorgadze.,DNA Photonics: Spectroscopic and Thermodynamic Methods for Studying Nanotechnological Abilities of DNA in Biomedical Research, Proceedings of the Fourth International Conference of European Academy of Science, pp. 102-103, (2019)
2018
- L. Lomidze, T. H. Williford, K. Musier-Forsyth, B. Kankia, “Isothermal amplification of long DNA segments by quadruplex priming amplification” Analytical Methods 10, 2972 (2018).
- O. Rcheulishvili, L. Tsverava, A. Rcheulishvili, M. Gurielidze, R. Solomonia N. Metreveli, N. Jojua, H-Y Holman; „Heavy metals specific proteomic responses of a highly resistant Arthrobacter globiformis 151B“; Annals of agrarian Sciences; 2018
2017
Articles:
Book Chapter:
- P. Midodashvili and M. Gogberashvili, “The LIGO Signal GW150914 within the Braneworld Scenario”.
- Gravitational Waves: Explorations, Insights and Detection (Physics Research and Technology). Nova Science Pub Inc, 2017. (ISBN: 978-1-53612-246-6). (pp.71-84).
2016
- B. Kankia, D. Gvarjaladze, A. Rabe, L. Lomidze, N. Metreveli, K. Musier-Forsyth, “Stable domain assembly of monomolecular DNA quadruplex: implications for DNA-based nanoswitches” Biophys. J. 110, 2169-2175 (2016).
- L. Lomidze, S. Kelley, S. Gogichaishvili, N. Metreveli, K. Musier-Forsyth, B. Kankia, “Sr2+ induces unusually stabled(GGGTGGGTGGGTGGG) quadruplex dimers” Biopolymers 105, 811-818 (2016).
- V. G. Bregadze, Z. G. Melikishvili, T. G. Giorgadze, I. G. Khutsishvili, T. B. Khuskivadze, Z. V. Jaliashvili and K. I. Sigua., Laser – Induced Fluorescence Resonance Energy Transfer for Analysis of Quality of DNA Double Helix, Laser Phys. Lett. 13 115601 (7pp), 2016.
- Vasil G. Bregadze, Zaza G. Melikishvili, Tamar G. Giorgadze, Irine G. Khutsishvili1,, Temur B. Khuskivadze, Zaza V. Jaliashvili, Absorption Spectroscopy of Silver Atoms and Nanomolecular Studies of DNA and Some Organic Structures, 2016 XXI International Seminar/Workshop on Direct and Inverse Problems of Electromagnetic and Acoustic Wave Theory (DIPED) pp.145-149, 2016.
- Midodashvili P. and Gogberashvili M., “Diffractions from the brane and GW150914”. Europhys. Lett. 114 (2016) no.5, 50008.
2015
- Quadruplex-and-Mg2+ (QMC) connection of DNA; B. Kankia; Sci. Rep. 5, 12996;
- Quadruplex priming amplification (QPA) for nucleic acid diagnostics; B. Kankia; in RNA and DNA Diagnostics, V.A. Erdmann, S.Jurga, J.Barciszewski, Ed. Springer, 281-295 (2015).
- Exponential quadruplex priming amplification for DNA-based isothermal diagnostics; T. Partskhaladze, A. Taylor, D. Gvarjaladze, L. Lomidze,B. Kankia; Biopolymers 103,88-95 (2015).
- Genetic Recombination of the rpoB Gene as a Mechanism of the Mycobacterium tuberculosis Resistance to Rifampin; Levan Lomidze, Mamuka Kotetishvili; Asian Journal of Pharmacy, Nursing and Medical Sciences, Vol 3, No 2, pp. 23-32. (2015)
- The Uptake and detoxification of Chromium by bacteria of Arthrobacter species and the influence and of different metal ions on these processes; Olia Rcheulishvili, Tamaz Kalabegishvili, Hoi-ving Holman, Nino A. Rcheulishvili, Dimitri M.Papukashvili, Nunu Metreveli, Alexander Rcheulishvili; Conference Paper. Conference: The 8th international Workshop on Contaminant Bioavailability in the Terrestrial Environment., At Nanjing, China, October 2015.
2014
- Isothermal amplification of DNA using quadruplex primers with fluorescent pteridine base analogue 3-methyl isoxanthopterin” Sh. Gogichaishvili, J. Johnson,D. Gvarjaladze, L. Lomidze,B. Kankia, Biopolymers 101, 583-590 (2014).
- Thermodynamic properties of quadruplex primers for highly versatile isothermal DNA amplification”J. Mathias, R. Okyere, L. Lomidze, D. Gvarjaladze, K. Musier-Forsyth, B. Kankia, Biophys. Chem. 185, 14-18 (2014).
- Quadruplex priming amplification combined with nicking enzyme for diagnostics”Sh. Gogichaishvili, L. Lomidze,B. Kankia, Anal. Biochem. 466, 44-48 (2014).
- Accumulation and Distribution of Cd, Zn, Cu and Mn in Barley; Rcheulishvili O, Metreveli N, Kalabegishvili T, Rcheulishvili A, Abashidze A, Korpela T, Tugushi L; Georgian Engineering News, №3, 2014, pp 7-12.
- Localization of Matter Fields in the 6D Standing Wave Braneworld. Pavle Midodashvili. Int.J.Theor.Phys.53(2014) 1174-1187.
- Study of cadmium distribution and accumulation in saffron; Rcheulishvili O, Rcheulishvili A, Osefashvili M, Papukashvili D, Tugushi L, Metreveli N; Proceedings Of the Georgian Academy of Sciences, v.39, N3-4, (2014).
- New Class of N-dimensional Braneworlds. Pavle Midodashvili, Merab Gogberashvili and Giorgi Tukhashvili. Gen.Rel.Grav. 46 (2014) 1697.
- Fermions in the 5D Gravity-Scalar Standing Wave Braneworld. Pavle Midodashvili and Merab Gogberashvili. Int.J.Mod.Phys. A29 (2014) 24, 1450141.
2013
- J. Johnson, R. Okyere, A. Joseph, K. Musier-Forsyth, B. Kankia, “Quadruplex formation as a molecular switch to turn on intrinsically fluorescent nucleotide analogs” Nucleic Acids Res. 41, 220-28 (2013).
- A. Taylor, A. Joseph, R. Okyere, Sh. Gogichaishvili, K. Musier-Forsyth, B. Kankia “Isothermal quadruplex priming amplification for DNA-based diagnostics” Biophys. Chem. 171, 1-8 (2013).
- O. Rcheulishvili, N. Datulishvil, I. Gabriadze, T. Kutateladze, D. Pataraya, M. Gurielidze, N. Metreveli; Effect of Chromate on DNA of Arthrobacter globiformis; Nano-Studies, 7, 2013.
- O. Rcheulishvili, L. Tugushi, E. Gelagutashvili, A. Rcheulishvili, N. Rcheulishvili, D. Papukashvili; “The Accumulation of Cadmium by Saffron (Crocus sativus L), coriander (Coriandrum sativum) and basil (Ocimum basilicum) from Cd enriched soil”, “Nano Studies”, 7, (2013).
2012
- UV Damage of Collagen: Insights from Model Collagen Peptides, Biopolymers, volume 97, issue 3, pages 189-198, (2012).
- Synthesis of Gold Nanoparticles by Some Strains of Arthrobacter Genera. Journal of Materials Science and Engineering A 2(2) (2012) 164-173.
- Localization of gauge bosons in the 5D standing wave braneworld. Phys. Lett. B707 (2012) 169.
- Localization Problem in the 5D Standing Wave Braneworld. Int.J.Mod.Phys. D21 (2012) 125008.
Staff
- Nunu Metreveli – Associate Professor, Director of the Institute
- Besik Kankia – Associate Professor
- Palve Midodashvili – Associate Professor
- Yuri Baghaturia – Associate Professor
- Olia Rcheulisvili – Researcher
- Levan Lomidze – Researcher
- Davit Gvarjaladze– Researcher
- Irine Khutsishvili- Researcher
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